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February 2008 February 29, 2008 LONDON (Reuters) - GlaxoSmithKline Plc's new breast cancer drug Tykerb is to go head-to-head with Genentech Inc's blockbuster Herceptin to see whether one is better or if patients should get both. Epoetin, darbepoetin linked to higher mortality, more VTEs in cancer patients February 26, 2008 NEW YORK (Reuters Health) - Erythropoiesis-stimulating agents are associated with increased risk of venous thromboembolism (VTE) and higher mortality rates when used to treat anemia in patients with cancer, according to meta-analyses published in the Journal of the American Medical Association for February 27. Combined breast screening provides best survival for BRCA1 mutation carriers February 26, 2008 NEW YORK (Reuters Health) - Among women with BRCA1 gene mutations, annual screening with both mammography and MRI is associated with better survival than with either screening modality alone, new research indicates. The downside, however, is a high rate of false-positive results and biopsies for benign disease. HPV-related oral carcinomas becoming more common February 26, 2008 NEW YORK (Reuters Health) - The incidence of oral squamous cell carcinomas (OSCCs) potentially related to human papillomavirus (HPV) appears to be increasing in the United States, researchers report in the February 1st issue of the Journal of Clinical Oncology. February 22, 2008 SOUTH SAN FRANCISCO - The Food and Drug Administration granted accelerated approval for Avastin (bevacizumab), in combination with Taxol (paclitaxel) chemotherapy, for the treatment of patients who have not received chemotherapy for their metastatic HER2-negative breast cancer. February 18, 2008 WASHINGTON (Reuters) - Uninsured Americans and those in a government health program for the poor are far more likely to have advanced diseases when diagnosed with cancer than those with private coverage, researchers said on Sunday. February 18, 2008 FRANKFURT (Reuters) - Bayer HealthCare, a U.S.-based unit of Bayer AG , said on Monday it had stopped a late-stage trial of Nexavar in patients with non-small cell lung cancer, after an independent data monitoring committee said it would not meet the main goal of improved overall survival. February 15, 2008 NEW YORK (Reuters Health) - Researchers have developed what they believe is the first blood biomarker test that accurately detects ovarian cancer at an early stage. February 15, 2008 NEW YORK (Reuters Health) - Hair from women with breast cancer can be distinguished from hair obtained from women without the disease, researchers in Australia report. February 14, 2008 NEW YORK (Reuters Health) - Racial differences in the incidence and mortality rates of prostate cancer appear to be driven by distinct patterns of gene expression in the tumor microenvironment, scientists report in the February 1 issue of Cancer Research. February 14, 2008 NEW YORK (Reuters Health) - Researchers have confirmed yet another ill effect of smoking cigarettes: it increases the risk of breast cancer in women with a common genetic variation. February 14, 2008 NEW YORK (Reuters Health) - Current evidence cannot definitively identify the best approach to clinically localized prostate cancer, according to findings of a systematic review reported in a February 4th early publication of the Annals of Internal Medicine. February 13, 2008 NEW YORK (Reuters Health) - A vaccine based on prostate stem cell antigen (PSCA) can provide long-term protection against prostate cancer in mice genetically predisposed to the malignancy, new research indicates. February 13, 2008 NEW YORK (Reuters Health) - Nodular lymphocyte-predominant Hodgkin's lymphoma (NLPHL), which expresses CD20, appears to be highly responsive treatment with rituximab, an approach that helps avoid late toxicities, according to German researchers. Anti-cancer effect of salpingo-oophorectomy differs by BRCA type February 11, 2008 NEW YORK (Reuters Health) - Risk-reducing salpingo-oophorectomy (RRSO) can help prevent breast and gynecologic malignancies in high-risk women, but the benefit depends on the woman's BRCA status, according to a report in the February 11th online issue of the Journal of Clinical Oncology. February 11, 2008 LONDON (Reuters) - Three studies published on Sunday identify at least ten new genes that raise a man's risk of prostate cancer, information that could lead to better screening and targeted drugs to treat the disease. February 11, 2008 NEW YORK (Reuters Health) - A new study suggests that a small number of Web sites dedicated to breast cancer offer inaccurate information, though the likelihood is greater with those that focus on alternative medicine. February 11, 2008 NEW YORK (Reuters Health) - Acute myeloid leukemia (AML) patients with a mutant variety of the Fms-like tyrosine kinase 3 (FLT3) gene may be particularly receptive to therapy with the kinase inhibitor sorafenib, the results of animal and clinical studies suggest. February 8, 2008 CHICAGO (Reuters) - A missing protein may explain why some skin cells advance to a deadly skin cancer known as melanoma instead of simply developing into harmless moles, U.S. researchers said on Thursday. February 8, 2008 NEW YORK (Reuters Health) - A combination of biomarkers detectable in urine more accurately detects prostate cancer than the standard PSA blood test and the newer PCA3 test, according to a report in the journal Cancer Research. February 7, 2008 LONDON (Reuters) - New data from a combined analysis of four Phase II/III studies involving more than 20,000 women confirm the effectiveness of Merck & Co Inc's cervical cancer vaccine Gardasil, researchers said on Thursday. February 7, 2008 NEW YORK (Reuters Health) - Expression of the blood protein osteopontin may be an independent prognostic marker for melanoma, clinicians report in the journal Cancer. February 6, 2008 NEW YORK (Reuters Health) - Although magnetic resonance imaging (MRI) of the breast provides advantages over mammography, and is increasingly used to evaluate candidates for breast-conservation treatment (BCT), it does not improve the outcome of BCT in women who have received radiation therapy for early-stage invasive breast carcinoma or ductal carcinoma in situ, according to a recent study. February 6, 2008 NEW YORK (Reuters Health) - The combination of permanent iodine-125 seed implants and carmustine (BCNU) wafers is safe and effective in patients with recurrent glioblastoma multiforme (GBM), according to a report in the February issue of the Journal of Neurosurgery. February 6, 2008 NEW YORK (Reuters Health) - A combination of two endoscopic ultrasound techniques provides a highly accurate method of staging the mediastinum in patients with suspected lung cancer, according to a report in the February 6th issue of the Journal of the American Medical Association. Copyright 2008 Reuters. Click for Restrictions.
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